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Treatment with ezetimibe should be initiated under the supervision of a physician at a specialist clinic

Cholesterol metabolism was found to exert catabolic functions in chondrocytes by upregulating matrix-degrading enzymes, leading to the development of arthritis (Figure 4) ( FIGURE 4 2.2.3.2 Natural products targeting cholesterol biosynthetic Berberine is hypothesized to suppress the inflammatory proliferation of RAFLSs by modulating AMPK/lipogenesis, LPA/LPA 1 /ERK/p38 MAPK ( + T cells induced by M1-exo ( 2.2.4 Fatty acids metabolism 2.2.4.1 Fatty acids metabolism in RA pathology Free fatty acids are present in the serum and synovial fluid of RA patients, and can impact joint tissues and immune cells involved in the pathophysiology of the disease

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Psychopharmacology (Berl) 2004;175(1):84-91

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